Detalhe da pesquisa
1.
Exebacase in Addition to Standard-of-Care Antibiotics for Staphylococcus aureus Bloodstream Infections and Right-Sided Infective Endocarditis: A Phase 3, Superiority-Design, Placebo-Controlled, Randomized Clinical Trial (DISRUPT).
Clin Infect Dis
; 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297916
2.
Safety and Pharmacokinetics of Exebacase in an Infant With Disseminated Staphylococcus aureus Infection.
Clin Infect Dis
; 75(2): 338-341, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34894129
3.
Exebacase Is Active In Vitro in Pulmonary Surfactant and Is Efficacious Alone and Synergistic with Daptomycin in a Mouse Model of Lethal Staphylococcus aureus Lung Infection.
Antimicrob Agents Chemother
; 65(9): e0272320, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34228536
4.
Development of a Broth Microdilution Method for Exebacase Susceptibility Testing.
Antimicrob Agents Chemother
; 65(7): e0258720, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33903102
5.
Efficacy assessment of lysin CF-296 in addition to daptomycin or vancomycin against Staphylococcus aureus in the murine thigh infection model.
J Antimicrob Chemother
; 76(10): 2622-2628, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34223628
6.
Exebacase Demonstrates In Vitro Synergy with a Broad Range of Antibiotics against both Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31712212
7.
Effect of the Lysin Exebacase on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis as Determined by Echocardiography.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32340988
8.
Postantibiotic and Sub-MIC Effects of Exebacase (Lysin CF-301) Enhance Antimicrobial Activity against Staphylococcus aureus.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936103
9.
Antimicrobial Activity of Exebacase (Lysin CF-301) against the Most Common Causes of Infective Endocarditis.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31332073
10.
The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670427
11.
Exebacase in Addition to Daptomycin Is More Active than Daptomycin or Exebacase Alone in Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31358593
12.
Correction for Oh et al., "Development of a Broth Microdilution Method for Exebacase Susceptibility Testing".
Antimicrob Agents Chemother
; 65(10): e0165821, 2021 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34533411
13.
Activity of Lysin CF-296 Alone and in Addition to Daptomycin in a Rat Model of Experimental Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33722889
14.
In vitro activity of exebacase against methicillin-resistant Staphylococcus aureus biofilms on orthopedic Kirschner wires.
BMC Res Notes
; 16(1): 209, 2023 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697424
15.
Direct Lytic Agents: Novel, Rapidly Acting Potential Antimicrobial Treatment Modalities for Systemic Use in the Era of Rising Antibiotic Resistance.
Front Microbiol
; 13: 841905, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35308352
16.
Locally delivered antistaphylococcal lysin exebacase or CF-296 is active in methicillin-resistant Staphylococcus aureus implant-associated osteomyelitis.
J Bone Jt Infect
; 7(4): 169-175, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36032801
17.
Arthroscopic "Debridement and Implant Retention" With Local Administration of Exebacase (Lysin CF-301) Followed by Suppressive Tedizolid as Salvage Therapy in Elderly Patients for Relapsing Multidrug-Resistant S. epidermidis Prosthetic Knee Infection.
Front Med (Lausanne)
; 8: 550853, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34055817
18.
Exebacase for patients with Staphylococcus aureus bloodstream infection and endocarditis.
J Clin Invest
; 130(7): 3750-3760, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32271718
19.
Tiotropium induced bronchodilation and protection from dynamic hyperinflation is independent of extent of emphysema in COPD.
Pulm Pharmacol Ther
; 22(3): 237-42, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19138754
20.
In vitro activity of Exebacase (CF-301) against clinical Staphylococcus aureus surveillance isolates from the United States, Europe, and Latin America, 2015-2017.
Diagn Microbiol Infect Dis
; 95(4): 114879, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31466875